For an oocyte for being Completely ready for fertilization and expansion into an embryo, the correct list of genes must be turned on. Namekawa suspected that this pre-programming of your oocyte genome occurs in several phases — the very first one starting off throughout the time a woman is born. He believed that chromatin remodeling proteins did much of this do the job, by shifting spools all around.
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Significant protein equipment, named chromatin remodelers, can change the positions of spools up and down the DNA thread, thus facilitating the expression — or silencing — of thousands of genes.
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